Playing as Scout allows you to evade Merasmus' attacks more easily than other classes due to your agility and ability to double and triple jump.
Hit-and-run tactics are a necessity when attacking Merasmus.
The Scout's agility, double and triple jumps allow him to evade Merasmus' magic attacks with more ease than other classes.
A Scout has the best chance of stunning Merasmus with a bomb due to his speed and agility. If the Bombinomicon chooses you as the bomb carrier, find Merasmus and charge at him!
The Scout's ability to get round the map quickly is vital when Merasmus hides as a prop.
Bonk! Atomic Punch will allow you to survive Merasmus' magic for a short time and also distract the boss effectively.
Because base damage is retained at all ranges when attacking Merasmus, the Scattergun will deal the most damage to him, provided you can move to around medium range to ensure you don't partially miss your shots.
The Pistol can be effective against Merasmus as base damage remains the same when attacking it. This will allow you to do more damage from a longer range than normal.
The Special Delivery can be very useful when trying to kill Merasmus, as the health bonus increases your survivability, and the Shortstop allows you to deal a good amount of damage at medium-range.
The Pretty Boy's Pocket Pistol is quite possibly the most harmful available weapon. Its health bonus is trivial at best against an enemy of such firepower, its firing speed penalty inhibits damage output, and its fire vulnerability is suicidal against Merasmus, whose main attack is fire-based. Fall damage immunity is trivial when the only attack causing such a circumstance is fire-based and fall damage can be escaped by double-jump.
The Soda Popper is an ineffective weapon to use as Merasmus does not take damage from mini-crits.
Do not use Crit-a-Cola against Merasmus. Your attacks will deal no extra damage and will make it easier for Merasmus to kill you.
The Sandman baseball and Fan O'War are ineffective against Merasmus as he cannot be stunned by baseballs or marked for death.
The Scout's health is low enough that a single blast from Merasmus' magic staff will likely result in death, even with the Special Delivery Set equipped.
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